Mid-table last season, Saints boss George Burley has been amongst the busiest managers in the Championship this summer, drafting in a host of players from at home and abroad, including Rudi Skacel for £1.6m from Hearts and Bradley Wright-Phillips for £1m from Manchester City.
Darrren Kenton, Yoann Folly and Paul Smith have been allowed to leave St Mary’s.
Southampton are 9/2 with Coral to win the Championship, 5/2 to be promoted and 25/1 to be relegated.
Striker Gregorz Rasiak is a 14/1 chance to be the top scorer in the division, while in Coral’s match bet market, Saints are 4/7 to finish ahead of Crystal Palace.